Research Neglected Diseases, The Challenges Encountered In Researching And Developing New Medicines For These Diseases. Describe the Markets That Are Involved and the Incentives That Are Used To Encourage The Development Of Medications …

Neglected Diseases


Most of the scholars describe how health, science, and technology are on the rise being identified as the important pillars of the social and economic development. However, with the increase in research and development, the infectious diseases are on the rise and have continued to affect the poor or the marginalized populations of the globe. The three factors that are attributed to the issue from the public point of view are; the absence of knowledge about the diseases, the ability to use the essential tools and others. The resulting outcomes are the neglected diseases such as Tuberculosis, HIV/AIDs, and malaria with which the public-private partnership have begun to solve the situations (Broadbent, 2011). The research will be based on neglected diseases in the society, controversies that are encountered in the global health and market-based solutions to eradicate the neglected diseases.

Neglected diseases

The neglected diseases are commonly known as the neglected tropical disease are a collection of contagious diseases that are spread among the poverty inflicted populations of the world such as the African and some Asian nations. According to the world health organization (WHO, 2010), the diseases can be described as the conditions that impact the people residing in the poorest nations in the world especially in the rural areas. Although the media and other organizations have concentrated on the three major diseases such as AIDs, TB, and malaria, various epidemic diseases such as river blindness, sleeping sickness, hookworm, elephantiasis, and schistosomiasis have been neglected to be focused on. Thus, the ignorance of the health officials and the lack of research and development based on this diseases have been the cause of their massive spread globally as well as being the cause of 500,000 on a yearly basis. The drugs have been left to the point that the patients are not taken care of and have no funds to buy the drugs.

Research and development challenges

Various factors have affected research and development for the neglected diseases. The cost of complete medical research in the developing nations has been estimated to be $1000 on a daily basis. The research and development require funding to understand the diseases, and therefore the absence of funds derails the information for most of these disorders. Moreover, the issues of insecurity in most of the developing nations have hindered the research and development of these diseases (Hotez et al, 2009). Additionally, the classification of diseases as major and minor hence creating priorities in the diseases, have made the health organizations focus more on malaria and neglecting elephantiasis as a killer as well.

The market incentives

The various incentive mechanisms initiated beginning with the 1983 United States legislation on the orphaned drugs which was later on introduced in other nations to fight the rare diseases. These factors have been described as pull and push incentives. The pull factors promote the research development indirectly by promoting the revenue abilities and reducing the expenditures. For example, the differential pricing, the improved market commitments, and the prize mechanism proposals. On the other hand, the push factors direct impact to the research expenditures and support to the drug discoveries.

The Non-market based solutions

The non-medical related solutions include factors like as product development partnership and the patent pools. As compared to the market-based solutions, these factors can delink the research and development from dividends and then allow the people and the relevant philanthropic sectors to take financial responsibilities for directly and also control the innovation programs. Therefore, to promote the neglected disease research and development policies, and continue to deliver modern medicines to the patients in the developing world, then the nation must separate debates on research from the dialogue on access to the Commercial IP-secured drugs (Moran, 2013).

The current discussion

The current discussions are heavily on the solution mechanism to the neglected diseases. The first conversation concerns the role of health system actors in the neglected disease control programs. This is based on the effective leadership management to control the diseases, especially in the developing nations. Moreover, the strategic and technical advisory groups for neglected diseases received a proposal for the additional diseases like snake bites and others to neglected disease list (Strong et al, 2005).

Recommendation to the ministry of health (MOH)

The neglected disease requires a strong leadership of the ministry of health to make sure that there is better coordination of the vertical programs. Moreover, to control the disease there, the ministry of health needs to create long terms and frequent services to ensure that it is managed. There should be increased study and research on the diseases to acquire knowledge and develop the best solution to diseases.


The neglected disease has been a threat to the national health demographics leading to uncontrolled deaths. It is vivid that most of the health departments have concentrated on solving significant diseases and neglecting others. This has led to patients dying from diseases like elephantiasis while others were also suffering from sleeping sickness. This is due to the absence of the understanding of the effect of the neglected diseases increasing the deaths of many people in the developing nations.


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