Identify a Research Or Evidence Based Article That Focusses Comprehensively On A Specific Intervention Or A New Diagnostic Tool For The Treatment Of Diabetes In Adults Or Children

Treatment Of Diabetes In Adults Or Children

Evidence-based practice project Paper on Diabetes


Diabetes is a disease that is marked by high levels in relation to blood glucose leading to a deficiency in the production of insulin or the actions of insulin. The existence of the two types of diabetes that is type I and II have made diabetes a major health concern in the entire globe. Even with the current increase in the incidence of diabetes among the adults, very little progress has been done on the pathophysiology, the possible treatment, and management. There have been researching and study on the treatment of the disease but nothing new has been released to the health societies for the treatment. Therefore, the medical experts have only come up with evidence-based treatment interventions in the bid to assist manage diabetes.

The interventions recommended for the treatment of diabetes in the adult population are diverse. They include control of the blood pressure and cholesterol level and an attachment to blood glucose. The issue of the control and management of diabetes has been related to the eating habits of various people leading to the rise of blood sugar level. Moreover, of significance is the dietary habits of the adults and due to that, the American diabetes association in conjunction with the world health organization recommended a standardized nutritional intervention plan in which the health providers had to develop for the adult’s patients. Furthermore, the evidence comments that the treatment- intervention for diabetes assumes that a compliance with such practices or therapies with the inclusion of others, can lead to a control or management of glucose high levels to achieve the recommended normal level. Consequently, even with the existing assumptions, there is further evidence that the adherence to the recommended management interventions can assist the adult’s patients to achieve the normal glucose levels.

Moreover, based on the studies of both Rojas and Gomes provides a recommendation rather than a modern treatment plan for the disease. Metformin is an oral antidiabetic drug used for the treatment of diabetes. Rojas and Gomes recommend that though metformin is an old method for the treatment of the disease, it is still the best method that should be embraced.

The research summary

Rojas and Gomes (2013) provide significant information on the treatment intervention of diabetes. The researchers have identified that the management of diabetes requires a perfect treatment intervention in order to achieve the glycemic and cardiovascular risk factors plans. Moreover, the other recommended treatment strategies such as nutritional therapies are also effective, but metformin which is an old medication is more effective in the treatment of diabetes. Metformin has gained support not only because of its anti-hyperglycemic properties but also due to its efficiency in controlling and increasing the functionality of homeostasis, insulin resistance and redistribution of fats and other materials that might hinder the performance of insulin in the patient’s body.

Metformin in the treatment of adult diabetic patients

According to Rojas and Gomes, the current guidelines from the American Diabetes Association and the American Association of clinical Endocrinologist recommend an early initiation of metformin as a first line medicine for monotherapy and an additional therapy for patients diagnosed of T2DM. The recommendation decision was based on various factors such as glucose lowering effects which assist the patients in controlling the level of glucose in their bodies, the minimal level of side effects for the patient under medication such as the absence of gaining weight. Moreover, it’s affordable which makes more useful to most patients especially the ones coming from financially unstable families. Additionally, the first-line position of the drug was emphasized by the United Kingdom Prospective diabetes study (UKPD). This study according to the authors was based on risk reduction of the drug upon usage. This is based on a comparison to the ever existing life intervention and in consideration of the mean baseline body mass index (BMI). The best and factual evidence to a potential role of Metformin in the prevention of the Type II diabetes originates from Diabetes prevention program (DPP) tests.

Metformin with Placebo

According to the DPP study, the patients were observed between 3-4 weeks washout duration. In was found that diabetes increased from 25 to 30% in the group using the metformin while in the placebo group it increased from 33 to 36% among the adults. It is vivid that metformin still provides a decreased diabetes incidence (Risk ratio 0.75 and p 0.005). This information suggests that metformin may assist to delay the onset of diabetes. The study was performed with adult patients only and has a BMI that is more than 35 kg/m2.


The medical experts have provided various interventions to replace the lifestyle in case of failure. The pharmacological therapy becomes a significant resource in the prevention of type 11 diabetes in adults. According to the researchers, various drugs have been tested to match the requirement and metformin among many drugs have got the most recommendation. The evidence-based researches were conducted by various bodies in the test for the best drug to control the disease.


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